Schizophyllum commune Exopolysaccharides Salmonella Infection In Vitro Data

Parameth Thiennimitr's 132.8 KB dataset investigates fungal exopolysaccharides from Schizophyllum commune CMU-01. Agar well diffusion, liquid culture, gentamicin protection assays, and qPCR were used on T84 gut epithelium and RAW264.7 macrophages. The data reveals no direct antimicrobial effect but shows immunomodulatory activity reducing Salmonella invasion and promoting macrophage M1-polarization.

Use Cases

• Analyze indirect immunomodulatory effects of mushroom extracts based on gentamicin protection assay data
• Investigate macrophage polarization patterns based on cytokine gene expression data
• Compare anti-Salmonella activity across different extract forms based on agar well diffusion and liquid culture results

Strengths

• Data is from a specific fungal strain (Schizophyllum commune CMU-01)
• Results are derived from multiple in vitro assays (agar well diffusion, liquid culture, gentamicin protection, qPCR)
• Dataset is licensed under CC-BY-4.0 for open reuse

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data is limited to in vitro cell models (T84 and RAW264.7) and may not reflect in vivo conditions

Provenance

Source

figshare

Collection Method

Experimental data from in vitro assays

Freshness

Last updated 2026-04-09 05:30:35