Litopeidin Antiviral Activity Data Against Anguillid Herpesvirus in Eels

Figshare dataset by yingyi Duan, last updated May 29, 2026, presents experimental results on the antiviral peptide Litopeidin28-51. The 573.7 KB XLSX file contains data from in vitro and in vivo studies on Anguilla rostrata, measuring survival rates and molecular markers of ferroptosis. The work investigates the peptide's mechanism via the Keap1/Nrf2/GCLC/GPX4 pathway.

Use Cases

• Modeling the dose-response relationship of Litopeidin28-51 based on the reported 19.1% increase in eel survival rate.
• Analyzing correlations between molecular markers like iron accumulation, lipid peroxidation, and viral pathology severity mentioned in the description.
• Validating computational models of host-pathogen interaction based on the described Keap1-Nrf2 binding and Nrf2 pathway activation data.
• Benchmarking new antiviral compounds against the peptide's performance metrics described in the in vivo infection model.

Strengths

• Dataset is openly licensed under CC-BY-4.0, permitting broad reuse.
• Description provides a specific, quantified result: a 19.1% increase in infected eel survival rate.
• Mechanistic pathway (Keap1/Nrf2/GCLC/GPX4) is explicitly detailed, providing context for the data.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale at 573.7 KB, indicating limited scope.

Provenance

Source

yingyi Duan via figshare.

Collection Method

Experimental data from in vitro and in vivo studies using an Anguilla rostrata viral infection model.

Freshness

Last updated 2026-05-29 09:43:35; freshness should be verified.