Methodological Quality Scores for Borderline Personality Disorder Treatment Guidelines

Three major clinical practice guidelines for Borderline Personality Disorder treatment were evaluated for methodological quality using the AGREE-II instrument. The dataset contains scores across six domains, including rigor of development and applicability, for guidelines from NICE (UK, 2024), APA (US, 2025), and a German guide (2022). Fiorella Alvarez Arias compiled this data in a 2026 scoping review.

Use Cases

• Compare AGREE-II domain scores like 'rigor of development' and 'applicability' across NICE, APA, and German guidelines to identify methodological strengths and weaknesses.
• Analyze the 'global scores' (NICE 93%, DGPPN-German 86%, APA 71%) to rank guideline quality and inform adoption decisions.
• Examine the 'intraclass correlation coefficients' data to assess the reliability of the quality appraisal process between independent reviewers.
• Synthesize recommendations data on first-line psychotherapy and psychopharmacology to map consensus and variation in treatment advice.

Strengths

• Direct comparison of three major international guidelines (NICE, APA, German) using a standardized instrument (AGREE-II).
• Provides specific percentage scores for six quality domains, enabling granular analysis of methodological strengths like 'scope and purpose' and weaknesses like 'applicability'.
• Data is derived from a systematic review of 1,747 records, following a transparent selection and appraisal methodology.

Limitations

• The dataset is extremely small, containing quality assessment data for only three clinical guidelines.
• Temporal coverage is limited to guidelines published or updated between 2020 and 2025, excluding earlier influential versions.
• Geographic representation is narrow, covering only the United Kingdom, United States, and Germany.

Provenance

Source

Systematic search in Medline, Embase, Scopus, and guideline-developing organizations.

Collection Method

Scoping review with two independent reviewers using the AGREE-II instrument for appraisal.

Time Range

Guidelines published or updated between 2020 and 2025.

Freshness

Includes guidelines updated as recently as 2025; dataset itself was last updated in April 2026.

Geography

Guidelines from the United Kingdom (NICE), United States (APA), and Germany (DGPPN).