Nathalia Rocco Machado published data on April 27, —, investigating the role of cysteine oxidation in CaMKIIδ and cardiac injury. The dataset includes results from transgenic mouse models (CaMKIIδC273S) assessing cardiac function at rest, during dobutamine stress, and after ischemia-reperfusion in the Langendorff model. The 2.5 MB dataset contains files in PRISM and DOCX formats.
Use Cases
- Analyze the protective effect of the Cys273Ser mutation on cardiac function based on the described functional assessments.
- Compare infarct size between wild-type and transgenic mouse hearts following ischemia-reperfusion based on the described experimental model.
- Investigate the relationship between CaMKIIδ oxidation and autonomous activation based on the described molecular mechanism.
- Evaluate potential drug targets focused on Cys273 for human cardiac disease based on the conclusion stated in the description.
Strengths
- Dataset is 2.5 MB, facilitating quick download and inspection.
- Includes data from a specific transgenic mouse model (CaMKIIδC273S) and a controlled experimental protocol (Langendorff model).
- Published under a public domain (us-pd) license, allowing for unrestricted reuse.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Description metadata is limited; actual data quality requires manual inspection after download.
Provenance
- Source
- figshare, author Nathalia Rocco Machado.
- Collection Method
- Data likely generated from laboratory experiments involving transgenic mouse models, cardiac function assessments, and the Langendorff ischemia-reperfusion model.
- Time Range
- null
- Freshness
- Last updated 2026-04-27 13:23:01; freshness should be verified.
- Geography
- null