PerturbPair: Dual-Modality Platform for Cellular Response Mapping

A 7.7 GB dataset integrating Perturb-seq and optical pooled screening to map cellular responses and enable cross-modal inference. The dataset is stored in H5AD format and was authored by Romain Lopez, last updated on 2026-04 18.

Use Cases

• Train models for cross-modal inference between genetic and optical perturbation readouts.
• Analyze cellular response patterns to various perturbations based on the integrated dual-modality platform.
• Benchmark multimodal data integration methods for single-cell genomics.
• Map gene expression changes to phenotypic outcomes using the combined Perturb-seq and optical screening data.

Strengths

• Dataset size of 7.7 GB suggests substantial data volume.
• Integrates two distinct modalities (Perturb-seq and optical pooled screening) for a more complete view.
• Released under a permissive CC-BY-4.0 license.
• Last updated date of 2026-04-18 indicates recent maintenance.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, authored by Romain Lopez.

Collection Method

Likely generated from laboratory experiments integrating Perturb-seq and optical pooled screening.

Time Range

null

Freshness

Last updated 2026-04-18 21:51:58.

Geography

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