Porcine Biventricular Pressure-Volume Loop Data from Endotoxic Shock Experiments

Processed pressure-volume loop analysis results from a porcine model of endotoxic shock with hemodynamic resuscitation, supporting a 2026 journal article. The dataset includes nine CSV files with averaged hemodynamic variables and dyssynchrony indices for left and right ventricles across four experimental stages. Data were collected from 15 Yorkshire pigs instrumented with high-fidelity conductance catheters.

Use Cases

• Modeling biventricular ejection fraction determinants based on loading conditions and contractility variables.
• Analyzing mechanical dyssynchrony indices (DYS, IFF) across systole and diastole phases.
• Studying hemodynamic variable responses (Ees, Ea, VAC, etc.) to endotoxic shock and resuscitation stages.
• Comparing left and right ventricular function under controlled experimental conditions.

Strengths

• Includes data from 150 left ventricular and 105 right ventricular occlusion recordings.
• Covers four predefined experimental stages: baseline, shock, fluid resuscitation, and norepinephrine restoration.
• Variables include key hemodynamic indices (EF, SV, dP/dtmax, tau, PRSW) and mechanical dyssynchrony metrics.
• Detailed variable glossary and methods are provided in the README and published article.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect bias inherent to the specific porcine model and experimental protocol.

Provenance

Source

figshare, supporting the article 'Loading conditions rather than contractility primarily determine biventricular ejection fraction in endotoxic shock' (Monge García et al., AJP-Heart Circ Physiol, 2026).

Collection Method

Data recorded from high-fidelity biventricular conductance catheters in a porcine model, analyzed beat-by-beat and aggregated per animal–stage.

Time Range

Experimental stages include baseline, established endotoxic shock, after fluid resuscitation, and after norepinephrine-mediated restoration.

Freshness

Last updated 2026-04-27 17:59:45; freshness should be verified.

Geography

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