PpD Study Raw Data: PAK4-targeting PROTAC Effects in Bladder Cancer

Raw data from a study investigating the PAK4-targeting PROTAC drug PpD in bladder cancer. The dataset includes RNA-seq results and mice data, showing that PAK4 knockout and PpD treatment significantly inhibited bladder cancer cell growth. The data was uploaded by Shan Xu to figshare in April 2026 under a CC-BY-4.0 license.

Use Cases

• Analyze PAK4's role in regulating cell cycle and apoptosis based on RNA-seq results mentioned in the description
• Validate drug efficacy by comparing PAK4 knockout and PpD-treated groups using the mice data
• Investigate PROTAC drug mechanisms in bladder cancer models based on the described experimental data

Strengths

• Data is openly licensed (CC-BY-4.0) for reuse.
• Includes both molecular (RNA-seq) and in vivo (mice) experimental results.
• File size is 17.4 MB, indicating a manageable download.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Shan Xu via figshare.

Collection Method

Likely contains experimental data from RNA sequencing and mouse model studies.

Time Range

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Freshness

Last updated 2026-04-09 08:51:35; freshness should be verified.

Geography

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