Super-Resolution Visual ProteomEx: H3K27me3 ChIP-Seq Data for Hard Tissues

ChIP-seq data for the histone modification H3K27me3, processed from raw sequencing reads for GCMN and MM samples. The dataset includes aligned BAM files, normalized BigWig signal tracks, and analysis of enrichment at transcription start sites for proteins like ELN and EHD2. It was authored by Kiryl Piatkevich and last updated on April 13, 2026.

Use Cases

• Assess H3K27me3 enrichment at transcription start sites based on the described analysis of downregulated proteins.
• Compare epigenetic signal distribution across samples using the generated BigWig tracks and correlation analysis.
• Visualize locus-specific ChIP-seq signals for candidate genes like ELN and EHD2 using the provided data tracks.

Strengths

• Data processing is detailed, mentioning specific tools like Bowtie2, Picard, and deepTools.
• Includes analysis focused on specific genomic regions (transcription start sites ±3 kb) for downregulated proteins.
• File size is 177.2 MB, indicating a medium-scale dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Sequencing reads were processed from raw data using FastQC, fastp, Bowtie2, Picard, SAMtools, and deepTools.

Freshness

Last updated 2026-04-13 01:54:51; freshness should be verified.