Mouse Cartilage Response to Type IX Collagen Deficiency and Exercise, 2026

Supplemental tables and figures from a 2026 study on articular and growth plate cartilage in mice. The data likely contains measurements from 12-week-old female wild-type and Col9a1-/- mice subjected to a six-week treadmill exercise protocol. The dataset was authored by Anja Niehoff and shared under a CC-BY-4.0 license.

Use Cases

• Analyzing the effects of mechanical loading on cartilage thickness based on the described forced running exercise protocol.
• Comparing extracellular matrix protein levels (e.g., matrilins, COMP) between wild-type and collagen-deficient mice.
• Investigating growth plate architecture alterations associated with type IX collagen deficiency.
• Studying localized, non-degenerative structural adaptations in articular cartilage under moderate exercise.

Strengths

• Dataset is associated with a peer-reviewed publication (American Journal of Physiology - Cell Physiology, 2026).
• Experimental design is clearly described, involving 10-12 mice per group across four conditions.
• Data is openly shared under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (492.3 KB), indicating limited scope, likely containing only supplemental tables and figures.

Provenance

Source

figshare, authored by Anja Niehoff.

Collection Method

Data likely originates from a controlled laboratory experiment with mouse models and biomechanical testing.

Time Range

Study published in 2026; experimental timeframe is not specified.

Freshness

Last updated 2026-05-03 12:47:59; freshness should be verified.

Geography

Laboratory study; geographic location is not specified.