Steroid-Naïve Asthma Patient Data on Blood Eosinophils and Oscillometry

A retrospective analysis of 57 adult patients with steroid-naïve asthma who underwent oscillometry at baseline and after 12 weeks of inhaled corticosteroid–based therapy. The dataset, authored by Osamu Matsuno and last updated in 2026, compares percentage changes in oscillometric parameters between patient groups stratified by baseline peripheral blood eosinophil count. It was used to investigate whether baseline eosinophil levels predict early changes in airway mechanics.

Use Cases

• Analyze the relationship between baseline blood eosinophil count and oscillometric parameter changes based on the described patient stratification.
• Investigate early treatment response in steroid-naïve asthma patients based on the 12-week follow-up data mentioned.
• Compare the utility of spirometry versus oscillometry for assessing treatment response based on the findings discussed in the description.

Strengths

• Includes data from 57 adult patients with steroid-naïve asthma.
• Contains paired oscillometry measurements at baseline and after a 12-week treatment period.
• Patient groups are clearly stratified by a defined clinical biomarker threshold (≥300 vs <300 cells/μL).
• Analysis includes multiple oscillometric indices (R5, R20, R5–R20, X5, Fres, ALX).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small, at 643.0 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Retrospective analysis of patient records.

Freshness

Last updated 2026-04-28 15:31:18; freshness should be verified.