INM-Gem: NIR Fluorescent Prodrug Activation Data in Zebrafish Gallbladder Model

INM-Gem is a near-infrared fluorescent prodrug dataset for cancer theranostics, authored by Neha Jain and last updated on 2026-04 16. The dataset, 711.0 B in size, contains information on a benzyl-spacer-engineered prodrug that releases gemcitabine and emits fluorescence at 673 nm upon activation. It was characterized using a zebrafish gallbladder model to assess tissue penetration, background signal, and specificity.

Use Cases

• Modeling drug activation kinetics based on the described 1,6-elimination mechanism in tumor microenvironments.
• Analyzing fluorescence signal characteristics for bioimaging based on the 673 nm emission and 131 nm Stokes shift.
• Comparing tissue penetration and specificity of drug candidates based on the described zebrafish model studies.
• Developing dual-functionality platforms for therapy and diagnostics based on the described gemcitabine release and NIR turn-on fluorescence.

Strengths

• Dataset is associated with a novel, characterized prodrug (INM-Gem) with specific fluorescence properties (673 nm emission).
• Experimental results include comparative studies on tissue penetration, background signal, and specificity in a biological model.
• File format is CSV, which is widely accessible for analysis.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• Dataset size is 711.0 B, indicating a very limited scope of data.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Neha Jain.

Collection Method

Likely contains synthesized and characterized experimental data from a biomedical research study.

Time Range

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Freshness

Last updated 2026-04-16 02:13:58; freshness should be verified.

Geography

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