Bergamottin Pretreatment Data for Cisplatin-Induced Acute Kidney Injury in Mice

A dataset from a 2026 figshare upload by Xue-ping Yang investigating the protective effects of bergamottin against cisplatin-induced acute kidney injury in mice and human renal tubular HK-2 cells. The data likely contains experimental results on cytotoxicity, renal function, inflammatory cytokines, lipid peroxidation, and BACE-1 expression.

Use Cases

• Analyze bergamottin's protective effect on renal function based on cytotoxicity and renal function evaluation data
• Investigate the role of BACE-1 in ferroptosis based on molecular docking predictions and expression data
• Compare synergistic effects of bergamottin with different cell death inhibitors based on in vitro cytotoxicity assays
• Model the interaction between bergamottin and BACE-1 residues based on hydrogen and hydrophobic interaction data

Strengths

• Data is associated with a specific pharmacological study published in 2026
• Includes in vitro (HK-2 cells) and in vivo (mouse model) experimental results
• Available in multiple file formats (XLSX, DOC, PDF) totaling 2.2 MB

Limitations

• Row count and column-level documentation are unknown, limiting suitability assessment
• The dataset is small (2.2 MB), which may constrain statistical analysis
• Data may reflect the specific experimental bias inherent to the single study methodology

Provenance

Source

figshare upload by Xue-ping Yang

Collection Method

Generated from laboratory experiments on mice and human renal tubular HK-2 cells

Freshness

Last updated 2026-04-13 01:20:05