STS-135 Space-flown Mouse Skin: Gene Expression and Metabolic Response

NASA's National Aeronautics and Space Administration examined changes in mouse skin after space flight. The data characterizes gene expression profiles related to oxidative stress and ECM remodeling, along with metabolic effects. The dataset was last updated on March 13, 2026.

Use Cases

• Identify biomarkers of oxidative stress in skin tissue based on gene expression profiles.
• Study extracellular matrix (ECM) remodeling pathways altered by spaceflight conditions.
• Model metabolic changes in mammalian tissues exposed to microgravity.
• Compare spaceflight-induced transcriptomic changes to terrestrial models of stress.

Strengths

• Data originates from a controlled spaceflight mission (STS-135) conducted by NASA.
• Focuses on specific biological processes: oxidative stress and ECM remodeling in skin.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Experimental analysis of mouse skin tissues from the STS-135 spaceflight mission.

Freshness

Last updated 2026-03-13 19:25:37.527053; freshness should be verified.