Hemodynamic and BOLD Simulations from Realistic Microvascular Models for Humans and Mice

Software and simulation data used to generate hemodynamic and BOLD responses in vascular anatomical networks representing the mouse somatosensory cortex. The data includes the first human VAN model with estimates of cerebral microvascular structure and accompanying simulations. Grant Hartung published this data on Harvard Dataverse, with a last update recorded for 2026-06-25.

Use Cases

• Validate biophysical models of neurovascular coupling based on simulated hemodynamic responses.
• Compare hemodynamic response functions between species based on the included mouse and human vascular models.
• Benchmark fMRI analysis algorithms using the provided simulated BOLD signal data.
• Study the impact of microvascular anatomy on BOLD signals based on the vascular network structure.

Strengths

• Includes the first ever human vascular anatomical network model for cerebral microvasculature.
• Provides accompanying source code and graphical user interfaces for re-simulation.
• Data is described in detail in an adjoining peer-reviewed publication.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and dataset size are unknown, which may limit suitability assessment.
• Last updated 2026-06-25 13:29:41; freshness should be verified.

Provenance

Source

Harvard Dataverse

Collection Method

Computational simulation and reconstruction based on vascular anatomical models.

Freshness

Last updated 2026-06-25 13:29:41.