Bis(oxazoline)-Cu(II) Catalyzed Asymmetric Conjugate Addition Data

A dataset from figshare containing results for a chiral bis(oxazoline)-Cu(II) complex-catalyzed asymmetric 1,4-conjugate addition reaction. The data, uploaded by Jing-Jing Zhai in April 2026, likely includes metrics for the synthesis of enantioenriched 3-indolyl derivatives. The file is 22.0 MB in size and is shared under a CC-BY-NC-4.0 license.

Use Cases

• Training ML models to predict enantioselectivity (ee) based on reaction conditions described in the summary.
• Analyzing the relationship between catalyst systems and diastereoselectivity (dr) outcomes mentioned in the description.
• Benchmarking synthetic methodologies for constructing congested quaternary and tertiary stereocenters, as referenced in the work.

Strengths

• The description reports excellent efficiency metrics, including up to >20:1 dr and 99% ee.
• File size is 22.0 MB, suggesting a contained and likely manageable dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Likely contains experimental results from the described catalytic chemistry research.

Time Range

Publication date suggests data is from work completed circa 2026.

Freshness

Last updated 2026-04-14 17:08:39; freshness should be verified.

Geography

Organization is unknown; geographic coverage cannot be determined.