Bisbenzoselenophene-Fused AzaBODIPYs: Photodynamic Therapy Photosensitizer Data

A dataset from figshare authored by Ziyu Zhang, last updated in June 2026, describes novel photosensitizer compounds for cancer photodynamic therapy. The data likely contains measurements for two selenium-incorporated azaBODIPY derivatives, including their near-infrared absorption properties and reactive oxygen species generation efficiency. In vivo results from a mouse tumor model are also referenced.

Use Cases

• Training models to predict reactive oxygen species generation quantum yields based on chemical structure features mentioned in the description.
• Analyzing the relationship between near-infrared absorption maxima (λ_max) and photocytotoxicity against specific cell lines like 4T1, B16, and HeLa.
• Evaluating the correlation between nanoparticle formulation and biocompatibility or dark toxicity metrics described in the study.

Strengths

• Includes specific performance metrics such as a reactive oxygen species generation quantum yield of 0.27 and a tumor growth inhibition rate of 73%.
• Describes in vitro results across three distinct cancer cell lines (4T1, B16, HeLa) and in vivo results from a 4T1-tumor-bearing mouse model.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small at 997.0 B, indicating limited scope.

Provenance

Source

figshare, author Ziyu Zhang.

Collection Method

Likely contains synthesized experimental data from the development and testing of novel chemical compounds.

Freshness

Last updated 2026-06-02 10:34:34; freshness should be verified.