bnAb Escape Sequencing and Scoring Data for HIV-1 Strains

Theodora Hatziioannou's dataset contains variant frequency and mutation scores for HIV-1 strains subjected to selection by broadly neutralizing antibodies 3BNC117 or 10-1074. The data is shared under a CC-BY-4.0 license as a 1.4 MB XLSX file on figshare, last updated in May 2026.

Use Cases

• Modeling HIV-1 escape pathways based on variant frequency data.
• Scoring the fitness impact of mutations under antibody pressure.
• Analyzing strain-specific responses to bnAbs 3BNC117 and 10-1074.

Strengths

• Data is shared under a permissive CC-BY-4.0 license.
• File size is 1.4 MB, indicating a focused and manageable dataset.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

Theodora Hatziioannou

Collection Method

Data from a study selecting HIV-1 strains with broadly neutralizing antibodies.

Freshness

Last updated 2026-05-12 07:02:29; freshness should be verified.