BraiDyn-BC: Mouse Neocortex Imaging and Behavior During Lever-Pull Learning

A multimodal dataset linking wide-field calcium imaging of the mouse neocortex to behavioral measurements during a motor skill learning task. It includes 15 sessions over two weeks from 25 mice trained to pull a lever for water rewards, with simultaneous high-speed videography and environmental monitoring. The dataset is formatted in the Neurodata Without Borders (NWB) standard and adheres to FAIR principles.

Use Cases

• Analyzing neural circuit dynamics underlying rapid within-session learning effects based on wide-field calcium imaging data.
• Investigating long-term behavioral adaptations based on comprehensive behavioral measurements and high-speed videography.
• Studying sensory-evoked neural responses based on the included resting-state and sensory-evoked activity data.
• Correlating cortical activity patterns with specific body, facial, and eye movements captured in video.

Strengths

• Multimodal data linking neural imaging (calcium) with comprehensive behavioral measurements.
• Data from 25 mice across 15 sessions spanning two weeks of learning.
• Formatted in the Neurodata Without Borders (NWB) standard, ensuring tool compatibility and FAIR adherence.
• Includes simultaneous high-speed videography capturing body, facial, and eye movements.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and file size are unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

BraiDyn-BC Database Project

Collection Method

Data collected from 25 mice trained on a cued lever-pull task, with simultaneous wide-field calcium imaging and high-speed videography.

Time Range

Sessions span two weeks of motor skill learning.

Freshness

Last updated date is unknown.

Geography

Laboratory setting; spatial coverage is not specified.