Markus Bredel et al. analyzed gene expression in a set of 50 human gliomas to identify functions and pathways linked to gliomagenesis. The dataset includes 31 pure glioblastomas, 14 tumors with oligodendroglial morphology, and 5 grade 1-3 astrocytomas, with 351 clones revealed as significantly linked to the disease.
Use Cases
- Classify glioma subtypes based on gene expression profiles mentioned in the description
- Identify biomarkers for gliomagenesis using the 351 significantly linked clones
- Train models to distinguish normal brain tissue from glioma samples
- Analyze pathways associated with oligodendroglial versus glioblastoma morphology
Strengths
- Includes 50 human tumor samples with clear subtype breakdown (31 GBM, 14 OG, 5 A)
- Analysis identified 351 gene clones significantly linked to gliomagenesis
- License is CC-BY-4.0, permitting broad reuse
Limitations
- Column-level documentation is absent; field semantics must be inferred after download
- Row count and file size are unknown, which may limit suitability assessment
- Last update date is unknown; freshness unverified
Provenance
- Source
- Markus Bredel et al.
- Collection Method
- Microarray analysis of tumor samples, with refined network knowledge applied.
- Time Range
- null
- Freshness
- null
- Geography
- null