BRIC-23 GeneLab: Staphylococcus aureus Omics Data from Spaceflight Experiment

NASA's BRIC-23 mission generated transcriptomic, proteomic, and metabolomic data for Staphylococcus aureus grown aboard the International Space Station. The dataset includes matched ground controls and a specific experiment to understand the effects of slow freezing on sample integrity. Data for the related organism Bacillus subtilis is deposited separately in GLDS-138.

Use Cases

• Compare microbial gene expression in space versus Earth based on transcriptomic data.
• Analyze protein abundance changes under spaceflight conditions using proteomic data.
• Study metabolic pathway alterations in microgravity using metabolomic data.
• Assess the impact of slow freezing protocols on omics data quality for future space experiments.

Strengths

• Data originates from a controlled NASA experiment on the International Space Station.
• Includes a specific control experiment designed to isolate the effect of slow freezing on data quality.
• Part of the GeneLab Reference Mission series aiming to produce high-quality omics data.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is stored in a BIN format, which may require specialized tools for access and analysis.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Samples of Staphylococcus aureus were grown aboard the International Space Station and compared to matched ground controls, with omics data generated post-flight.

Freshness

Last updated 2026-03-13 19:26:39.108038; freshness should be verified.

Geography

International Space Station and associated ground control locations.