Primary human fibroblastic reticular cell lines from three donors were treated with or without 10ng/ml interferon-gamma for four days and analyzed via bulk RNA sequencing. The dataset is a 28.0 MB CSV file published by Zoe Chua on figshare under a CC-BY-4.0 license. It was last updated on May 19, 2026.
Use Cases
- Identify differentially expressed genes in fibroblastic reticular cells based on interferon-gamma treatment.
- Analyze immune-related gene expression pathways based on the described cytokine stimulation.
- Compare transcriptional responses across the three donor cell lines mentioned in the description.
Strengths
- Data is derived from primary human cell lines from three distinct donors.
- Experimental conditions are precisely defined with a 10ng/ml interferon-gamma dose and a 4-day treatment period.
- Dataset is openly available under a permissive CC-BY-4.0 license.
Limitations
- Row count and column-level documentation are unknown, which limits suitability assessment.
- The dataset is relatively small at 28.0 MB, which may constrain the scope of analysis.
Provenance
- Source
- figshare
- Collection Method
- Bulk RNA sequencing of in vitro treated primary human cell lines.
- Freshness
- Last updated 2026-05-19 11:29:19; freshness should be verified.