Catalytic Amidation Screening Data for Carboxylic Acids and Amines

Veera K. Bruce-Salmenkivi published a dataset on figshare in May 2026 containing screening results for catalytic amidation reactions. The 133.3 MB ZIP file likely contains data from screening ortho-functionalized arylboronic acids as catalysts for the direct condensation of amines and carboxylic acids. The dataset identifies (2-(piperidin-1-yl)phenyl)boronic acid (2-PPBA) as an optimal catalyst for producing amides.

Use Cases

• Benchmarking catalyst performance based on the screening of ortho-functionalized arylboronic acids.
• Identifying reaction conditions for amide synthesis based on the described catalyst screening results.
• Developing machine learning models for catalyst discovery using the reported screening data.
• Studying structure-activity relationships for boronic acid catalysts based on the described ortho-substituted variants.

Strengths

• Dataset size is 133.3 MB, indicating a medium-scale collection of data.
• The dataset is licensed under CC-BY-NC-4.0, allowing for non-commercial sharing and adaptation.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Likely contains experimental screening data from catalytic amidation reactions.

Freshness

Last updated 2026-05-12 16:40:02; freshness should be verified.