CattleEpiMap: Epigenetic Atlas of 1,138 Bovine Genome Profiles

1,138 genome-wide epigenetic profiles from 53 adult tissues, five fetal tissues, and seven primary cell types provide a foundational resource for cattle functional genomics. This atlas from UC Davis includes chromatin accessibility, histone modifications, DNA methylation, and transcriptomes, enabling annotation of around 45% of the genome as putative regulatory elements. The data facilitates decoding of regulatory syntax and fine-mapping of GWAS loci for 22 complex traits.

Use Cases

• Training sequence-to-function deep learning models based on the described epigenetic profiles
• Fine-mapping GWAS loci for complex traits based on predicted variant impact from in silico mutagenesis
• Identifying tissue-specific regulatory elements based on chromatin accessibility and histone modification data
• Conducting cross-species comparative analysis of regulatory architecture based on evolutionarily conserved features

Strengths

• 1,138 genome-wide epigenetic profiles provide a broad scope of molecular data
• Data spans 53 adult tissues, five fetal tissues, and seven primary cell types
• Enables annotation of around 45% of the bovine genome as putative regulatory elements
• Includes multiple data types: chromatin accessibility, six histone modifications, CTCF binding, DNA methylation, chromatin conformation, and transcriptomes

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

UC Davis

Collection Method

Likely generated through laboratory assays and sequencing of bovine tissue and cell samples.

Time Range

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Freshness

Last updated 2026-03-22 03:16:36; freshness should be verified

Geography

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