CD37 HLI data

A 51.7 KB dataset published on figshare by Tessa Barrett on April 13, 2026. It contains transcriptomic and immune profiling data from a study investigating the role of the tetraspanin CD37 in critical limb-threatening ischemia (CLTI). The data likely includes results from murine hindlimb ischemia models and human muscle RNA-seq analysis.

Use Cases

• Analyzing macrophage reprogramming states based on transcriptomic signatures mentioned in the description.
• Investigating links between CD37 expression and inflammatory cytokine signatures in ischemic muscle.
• Modeling the impact of tetraspanin deficiency on muscle histologic repair and myofiber maturation.
• Comparing murine hindlimb ischemia model data with human PAD muscle RNA-seq profiles.

Strengths

• Data is associated with a specific, peer-reviewed research hypothesis on CD37 in CLTI.
• File is available in the widely accessible XLSX format.
• Dataset is published under a permissive CC-BY-4.0 license.

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download.
• The dataset is very small at 51.7 KB, indicating limited scope.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, authored by Tessa Barrett.

Collection Method

Likely contains experimental data from murine models and transcriptomic analysis of human muscle.

Time Range

Publication date is 2026; specific experimental time range is unknown.

Freshness

Last updated 2026-04-13 17:30:28; freshness should be verified.

Geography

Spatial coverage is not specified.