CD4 Melanoma TILs TCR Repertoires from Metastatic Lymph Nodes

T-cell receptor (TCR) repertoire data for sorted CD4 tumor-infiltrating lymphocytes derived from metastasized lymph nodes of melanoma patients. The dataset, 98.7 MB in size, was authored by Mikhail Goncharov and last updated on 2026-05-26. It is shared under a CC-BY-4.0 license.

Use Cases

• Compare TCR repertoires between CD39/PD-1 double-positive and non-double-positive T-cell subsets.
• Analyze T-cell clonality and diversity in metastatic melanoma lesions.
• Train models to predict T-cell phenotypes or tumor reactivity based on TCR sequence features.

Strengths

• Data is focused on a specific, clinically relevant cell population (sorted CD4 TILs from melanoma metastases).
• The dataset is 98.7 MB, suggesting a substantial volume of TCR sequence data.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect bias inherent to the specific patient cohort and source platform.

Provenance

Source

Mikhail Goncharov

Collection Method

Likely derived from sequencing sorted tumor-infiltrating lymphocytes.

Freshness

Last updated 2026-05-26 18:44:17; freshness should be verified.