Channel Trafficking Data: Membrane Insertion of Recombinant CaV1.2 Channels

Pilot study data on the membrane insertion of recombinant CaV1.2 calcium channels containing an extracellular bungarotoxin binding site motif. The data was contributed by Jared Kushner to the Jared Kushner AHA CDA Dataverse and was last updated on May 3, 2026. The specific volume and structure of the data are not detailed in the available metadata.

Use Cases

• Quantify membrane insertion efficiency based on bungarotoxin-fluorophore conjugate binding assays mentioned in the description
• Compare trafficking properties of recombinant CaV1.2 channels with and without the BBS motif described in the study
• Validate experimental protocols for measuring channel surface expression using the described fluorescent labeling technique

Strengths

• Data originates from a pilot study with a specific experimental focus on CaV1.2 channel insertion.
• The dataset has a specific last updated timestamp of 2026-05-03 19:20:00.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Jared Kushner AHA CDA Dataverse

Collection Method

Pilot studies using bungarotoxin-fluorophore conjugates.

Freshness

Last updated 2026-05-03 19:20:00; freshness should be verified