Chemical Composition and Efficacy of Alpinia Zerumbet Extracts on Staphylococcus Aureus

A study describes the antibacterial activity of essential oil and ethanol extract from Alpinia zerumbet leaves against Staphylococcus aureus strains isolated from cows with subclinical mastitis and standard ATCC strains. The work used the agar diffusion method with ten treatments at concentrations from 6.3 to 100.0 mg.mL-1 and identified major chemical constituents via chromatography. The results demonstrate complete inhibition of bacterial growth with 100 mg.mL-1 essential oil, showing potential for controlling bovine mastitis.

Use Cases

• Modeling dose-response relationships for plant extracts based on the described concentration levels (6.3-100.0 mg.mL-1).
• Analyzing correlations between specific chemical compounds (e.g., p-cymene, 1,8-cineole) and antibacterial efficacy mentioned in the description.
• Comparing the sensitivity of different bacterial strains (isolated vs. ATCC standard) to natural antimicrobial treatments.
• Screening plant-based compounds for mastitis control based on the described agar diffusion method and inhibition results.

Strengths

• The description specifies exact concentrations tested (100.0, 50.0, 25.0, 12.5, 6.3 mg.mL-1).
• Major chemical constituents are quantified with specific percentages (e.g., p-cymene at 32.72%).
• Results include a clear positive control outcome showing complete bacterial inhibition at 100 mg.mL-1.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Karina Neoob de Carvalho Castro via paperswithcode.

Collection Method

Experimental data from agar diffusion antimicrobial testing and chromatographic analysis (GC-MS/FID, HPLC-PDA).