clinfun: R Package for Clinical Trial Design and Analysis Functions

An R package named 'clinfun' provides utilities for designing and analyzing clinical trials. It contains functions for study designs such as Simon 2-stage and group sequential designs, and for data analysis including the Jonckheere-Terpstra test and survival quantile estimation. The package was authored by Venkatraman Seshan and is listed on the paperswithcode platform.

Use Cases

• Designing a Simon 2-stage clinical trial based on the described design functions.
• Implementing group sequential designs for interim analysis based on the package's utilities.
• Performing a Jonckheere-Terpstra test for trend analysis based on the described statistical functions.
• Estimating survival quantiles from time-to-event data based on the package's analysis capabilities.

Strengths

• Package provides specific, named statistical functions for clinical trial design and analysis.
• The description explicitly mentions two study design methods and two data analysis methods.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

Venkatraman Seshan

Collection Method

Software package development for R.