Clinical and Electroretinographic Profiles of 27 Stargardt Disease Patients in Brazil

A retrospective study of 27 patients with Stargardt disease treated at a Brazilian hospital between 1997 and 2014. The dataset includes clinical profiles and electroretinographic findings, such as visual acuity and age of symptom onset. It was authored by Letícia Schemberger Schafranski and is available via paperswithcode.

Use Cases

• Modeling disease progression based on clinical features like age of symptom onset and time to diagnosis.
• Analyzing correlations between electroretinogram results (amplitude, implicit time) and patient visual acuity.
• Characterizing the phenotypic spectrum of Stargardt disease based on fundus examination abnormalities.

Strengths

• Includes data from 27 patients, a specific cohort for a rare disease.
• Provides specific clinical metrics: visual acuity ranged from 0 to 1.6 logMAR with an average of 0.89 ± 0.42.
• Covers a long observation period from 1997 to 2014.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect geographic and institutional bias inherent to a single hospital in Brazil.

Provenance

Source

Complexo Hospital de Clínicas da Universidade Federal do Paraná’s Department of Ocular Electrophysiology and Neuro-Ophthalmology

Collection Method

Observational, retrospective study by analysis of patient records and electroretinographic examinations.

Time Range

1997 to 2014

Geography

Brazil