PM20D1 Biomarker Levels in Carotid Atherosclerosis Patients, 2018-2019

A prospective observational study of 231 carotid atherosclerosis patients and 231 healthy controls from July 2018 to December 2019. The dataset, described in an Open Access paper by Xincheng Huang, includes serum PM20D1 levels, demographic characteristics, and various inflammatory and lipid biomarkers. It was analyzed to investigate PM20D1's role as a potential biomarker for disease severity and plaque stability.

Use Cases

• Predicting carotid atherosclerosis severity based on serum PM20D1 levels mentioned in the description
• Analyzing correlations between PM20D1 and inflammatory markers like C-reactive protein and tumor necrosis factor
• Investigating plaque stability in atherosclerosis patients using biomarker profiles
• Building models to identify risk factors for carotid atherosclerosis from clinical and demographic variables

Strengths

• Includes a matched control group of 231 healthy individuals with the same BMI distribution as the patient cohort
• Contains multiple biomarker measurements per patient, including PM20D1, lipids, and inflammatory markers
• Data collection was prospective and observational over an 18-month period from July 2018 to December 2019

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Last update date is unknown; freshness unverified

Provenance

Source

Xincheng Huang via paperswithcode

Collection Method

Prospective observational study using blood samples and clinical records

Time Range

July 2018 to December 2019