Umbilical Cord Blood Biomarkers for Neonatal Respiratory Distress Syndrome

558 preterm infants were categorized into NRDS (n=162) and non-NRDS (n=396) groups in a retrospective single-center study. The dataset, authored by Qiuxiang Huang and last updated in 2026, measures soluble E-selectin and sVCAM-1 levels in umbilical cord blood and assesses their correlation with clinical outcomes.

Use Cases

• Predicting neonatal respiratory distress syndrome (NRDS) based on umbilical cord blood biomarker levels.
• Assessing the correlation between biomarker levels and clinical severity scores like the 5-minute Apgar score.
• Evaluating the prognostic value of biomarkers for 28-day outcomes in preterm infants.
• Developing logistic regression models to identify risk factors for poor prognosis in NRDS.

Strengths

• Includes data from 558 preterm infants, providing a substantial sample size for analysis.
• Reports specific performance metrics, including an AUC of 0.935 for combined biomarkers in predicting NRDS.
• Contains detailed statistical analysis results, including odds ratios and confidence intervals for risk factors.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect single-center bias inherent to the study design.

Provenance

Source

Qiuxiang Huang

Collection Method

Retrospective single-center study collecting umbilical cord blood samples from preterm infants.

Freshness

Last updated 2026-05-11 03:13:57; freshness should be verified.