ICI-Induced Pure Red Cell Aplasia in 32 Cancer Patients

A collection of 32 case reports on pure red cell aplasia (PRCA) induced by immune checkpoint inhibitors (ICIs) in cancer patients. The data was compiled by Jian Xiao from a systematic search of multiple medical databases up to July 2025. It includes patient age, time to PRCA onset, treatment cycles, and clinical management outcomes.

Use Cases

• Analyzing the temporal onset of PRCA based on the reported median time of 3 months after ICI initiation.
• Studying treatment outcomes based on interventions like glucocorticoid therapy and transfusion support.
• Profiling patient demographics based on the reported median age of 57.5 years.
• Investigating the relationship between treatment duration and PRCA incidence based on the median of 4 ICI cycles.

Strengths

• Includes data from 32 specific patient cases.
• Reports specific median values for age (57.5 years), time to onset (3 months), and treatment cycles (4).
• Source is a systematic review of multiple medical databases (PubMed, Embase, etc.).

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 51.6 KB, indicating limited scope.

Provenance

Source

figshare, author Jian Xiao.

Collection Method

Systematic search and retrospective analysis of published case reports.

Time Range

Case reports from the initiation of relevant research up to 11 July 2025.

Freshness

Last updated 2026-04-21 11:00:03; freshness should be verified.