Data on cocaine infusions earned by mice of two genotypes (wild-type and knock-down) across multiple sessions. The dataset covers two days preceding a dose-response challenge and two consecutive sessions during the challenge with varying cocaine doses. Author Matthew B. Pomrenze contributed this dataset, which is available via paperswithcode under an Open Access license.
Use Cases
- Modeling dose-response relationships for cocaine self-administration based on the described infusion counts at different doses (0.05, 0.1, 0.75, 2.0 mg/kg/infusion).
- Comparing behavioral patterns between wild-type (TRPC5 +/+) and knock-down (TRPC5 -/-) genotypes based on the described subject groups.
- Analyzing temporal patterns of drug intake by comparing infusion counts from days leading up to the challenge (-2, -1) with counts during the challenge sessions (S1, S2).
Strengths
- Includes data for two distinct genotypes (wild-type and knock-down), enabling comparative analysis.
- Captures behavioral data across a described range of four cocaine doses (0.05, 0.1, 0.75, 2.0 mg/kg/infusion).
- Provides temporal context with data from days preceding the challenge and specific sessions during the challenge.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Last update date is unknown; freshness unverified.
Provenance
- Source
- paperswithcode
- Collection Method
- Likely originates from a controlled laboratory experiment involving mouse self-administration.