Cognitive Impairment in Bipolar Disorder Compared to MCI and Dementia: Systematic Review

A systematic review of 1,461 articles, with 5 studies meeting inclusion criteria, comparing cognitive abilities in bipolar disorder (BD) to mild cognitive impairment (MCI) and dementia. Mario Simjanoski conducted the review, which found cognitive impairments in euthymic BD are as severe as or more severe than MCI, but less severe than Alzheimer's disease dementia. The review is registered with PROSPERO under ID CRD42020150412.

Use Cases

• Benchmark cognitive impairment severity in euthymic bipolar disorder based on the systematic review's findings.
• Compare cognitive domain deficits across psychiatric and neurodegenerative conditions based on the described review results.
• Inform study design for future clinical comparisons between BD, MCI, and dementia based on the identified research gap.

Strengths

• Systematic review methodology with a search of 1,461 articles and no year or language restrictions.
• Findings are based on a direct comparison of cognitive domains across three clinical conditions.

Limitations

• The underlying dataset (the review's included studies) is not directly accessible; only the review's summary is provided.
• Row count and column-level documentation for the aggregated study data are unknown.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Systematic literature review.