Mouse Behavioral and Immune Response Data Under Combined Space Stressors

A 2026 dataset from NASA investigates the combined effects of simulated galactic cosmic radiation, confinement, and altered gravity on 6-month-old female and male mice. The dataset includes results from flow cytometry assays on peripheral blood samples and behavioral and cognitive performance tests. It uses principal component analysis to represent total deficits and general linear models for prediction.

Use Cases

• Modeling behavioral deficit prediction based on early peripheral blood monocyte data.
• Analyzing independent and interactive effects of radiation exposure and housing conditions on cognition.
• Investigating sex-specific resilience to space stressors based on the reported resilience in female mice.
• Studying immune cell population dynamics in peripheral blood over time after irradiation and confinement.

Strengths

• First study investigating cumulative impacts of simultaneous space stressors.
• Includes data from both female and male mice under varied housing and radiation conditions.
• Uses principal component analysis and general linear models for integrated analysis of behavioral and biomarker data.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data is stored in a BIN format, which may require specialized tools for access.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Flow cytometry assay on blood samples from mice exposed to controlled space stressors.

Time Range

Data collection timeframe not specified.

Freshness

Last updated 2026-03-13 19:59:46.455923; freshness should be verified.

Geography

Laboratory study; geographic coverage not applicable.