Honeybee Brain Proteomics with Lysine Crotonylation Sites from Cold Exposure

3017 proteins with 15,233 lysine crotonylation sites identified via LC-MS/MS from adult honeybee brains. The dataset compares cohorts exposed to 8, 12, or 16 hours of cold during prepupal development against a control group, revealing differential modifications associated with cognitive impairment. The data was published by Chenyu Zhu on figshare in April 2026.

Use Cases

• Identify differentially modified lysine crotonylation sites based on cold exposure duration
• Analyze associations between pan-Kcr levels and learning/memory capacity from western blot results
• Investigate enrichment of proteins with modified Kcr in pathways like protein quality control and energy metabolism
• Validate key pathway proteins using parallel reaction monitoring data

Strengths

• Includes 15,233 identified lysine crotonylation sites across 3017 proteins
• Provides comparative data for four distinct treatment groups (CK, T8, T12, T16)
• Links quantitative proteomic data to behavioral assays of learning and memory

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

Data likely generated via LC-MS/MS proteomic analysis and western blot validation on honeybee brain samples.

Freshness

Last updated 2026-04-10 09:29:32