Lipoprotein and Metabolite Profiles for Rheumatoid Arthritis and Lupus Patients

Nuclear magnetic resonance spectroscopy was used to profile lipoproteins and metabolites in women with rheumatoid arthritis, systemic lupus erythethematosus, and healthy controls. The 37.9 KB dataset highlights disease-specific alterations in HDL and LDL particle sizes and concentrations, as well as metabolite levels like glutamine and alanine. Authored by Nancy Paola Duarte-Delgado and shared on figshare in March 2026, the data is provided in an XLSX format.

Use Cases

• Compare lipoprotein profiles between rheumatoid arthritis and systemic lupus erythematosus patients based on NMR-derived particle size and concentration data.
• Investigate correlations between LDL particle concentrations and disease activity scores (DAS28-ESR) in rheumatoid arthritis.
• Analyze associations between HDL particle measures and immune markers like complement C3 in systemic lupus erythematosus.
• Explore relationships between specific metabolites (e.g., glutamine, alanine, GlycB) and autoimmune disease status.

Strengths

• Data is derived from a specific analytical technique (¹H NMR spectroscopy) for lipoprotein and metabolite profiling.
• The description details specific, measurable findings such as reduced HDL particle size and lower concentrations of small HDL particles.
• The dataset is small (37.9 KB), making it quick to download and inspect.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• The dataset's scale is limited to a specific, likely small, cohort of female patients.

Provenance

Source

figshare

Collection Method

Data was generated using ¹H NMR spectroscopy on samples from patients and controls.

Freshness

Last updated 2026-03-17 18:21:02.