Comparison of Four Dental Anesthetic Latency Times from a Double-Blind Crossover Study

A double-blind, crossover, randomized study with 30 volunteers compared the latency times of Articaine, Lidocaine, Levobupivacaine, and Ropivacaine. The data were collected using a pulp tester at two-minute intervals after a posterior superior alveolar block, with statistical analysis performed using t-student, Friedman, and Kruskal-Wallis tests. The study, authored by Ana Carolina Saggin Britto, found no statistically significant differences in latency, with a median of two minutes for all anesthetics.

Use Cases

• Comparing the onset latency of different local anesthetics based on the pulp tester measurements described in the study.
• Analyzing the influence of gender on anesthetic latency time using the statistical results provided.
• Evaluating the methodology for determining pulp insensitivity in clinical trials based on the described testing protocol.
• Supporting decisions on anesthetic selection for oral surgery based on the reported identical median latency times.

Strengths

• Data originates from a double-blind, crossover, randomized study design, which suggests controlled experimental conditions.
• Statistical analysis included multiple tests (t-student, Friedman, Kruskal-Wallis) with a defined significance threshold (p<0.05).
• The study involved 30 volunteers undergoing 4 procedures each, providing a basis for within-subject comparison.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

Ana Carolina Saggin Britto

Collection Method

Double-blind, crossover, randomized clinical study using a pulp tester.