Complete Blood Cell Counts and Liver Lipidomics from Pla2g6 KO Mice

Walee Chamulitrat published this dataset on figshare in May 2026. It includes complete blood cell counts from aged male and female control and Pla2g6M-/- mice, categorized by splenomegaly response. The dataset also contains liver lipidomics data on fatty acids and phospholipids from young and old male iPLA2b/PLA2G6-null mice, along with original western blot images.

Use Cases

• Compare hematological parameters between control and Pla2g6 knockout mice based on complete blood cell counts.
• Analyze liver lipid composition changes with age based on lipidomics data from young and old knockout mice.
• Investigate correlations between splenomegaly status and blood profiles based on spleen weight to body weight groupings.
• Validate protein expression levels using the provided uncut western blot images.

Strengths

• Data is grouped by a specific biological metric: splenomegaly responders and non-responders based on spleen-to-body weight ratio.
• Includes multiple data modalities: tabular blood counts, lipidomics data, and raw western blot images.
• Released under a permissive CC-BY-4.0 license for broad reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small at 1.7 MB, potentially limiting the scope of analysis.

Provenance

Source

figshare

Collection Method

Likely generated from laboratory experiments on genetically modified mice.

Freshness

Last updated 2026-05-13 06:00:22; freshness should be verified.