Cryo-EM Structure of KCTD16-GABA-B2 Peptide Complex

A composite cryo-electron microscopy map and refined atomic model of the KCTD16 protein domain bound to a GABA-B2 receptor peptide. The dataset, created by Ning-En Chang, includes files deposited in the EMDB and PDB databases. It was last updated in April 2026.

Use Cases

• Analyze the atomic coordinates in the PDB file to understand the binding interface between KCTD16 and the GABA-B2 peptide.
• Use the composite cryo-EM map to validate the final refined model or for further density fitting and structural interpretation.
• Compare the provided structural model (PDB ID 9XNM) with related protein structures in public databases for evolutionary or functional studies.
• Extract spatial coordinates and B-factors from the CIF or PDB files for computational analysis of molecular dynamics or stability.

Strengths

• Data is linked to authoritative public repositories (EMDB and PDB) with specific accession codes (EMD-67028, EMD-67029, EMD-67030, EMD-67052, 9XNM).
• Includes both the final 3D atomic model and the composite cryo-EM map for cross-validation and interpretation.

Limitations

• The dataset is very small at 3.1 MB, containing only the specific composite map and model for one complex.
• No raw experimental data (micrographs, particle stacks) or intermediate processing results are included.
• The temporal and geographic context of the sample or experiment is not provided.

Provenance

Source

figshare, with primary data deposited in EMDB and PDB.

Collection Method

Generated via cryo-electron microscopy and subsequent 3D reconstruction and atomic model refinement.

Time Range

null

Freshness

Last updated in April 2026, indicating recent deposition.

Geography

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