Contezolid and PBNP Combination Synergy Against A. Baumannii

Experimental data from checkerboard tests and time-kill assays investigating the synergistic antibacterial activity of contezolid and polymyxin B nonapeptide (PBNP) against multidrug-resistant Acinetobacter baumannii strains. The dataset includes results from biofilm production assays and protective effect evaluations in MH-S cell and Caenorhabditis elegans nematode models. Author Dan rui Hao published this work on figshare under a CC-BY-4.0 license, last updated on 2026-05-25.

Use Cases

• Analyzing synergistic drug interactions based on checkerboard assay results.
• Evaluating the impact of drug combinations on bacterial biofilm production.
• Assessing the protective efficacy of drug combinations in cell culture and nematode infection models.

Strengths

• Data includes results from multiple experimental models: checkerboard, time-kill, biofilm, cell, and nematode assays.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small at 85.2 KB, indicating limited scope.

Provenance

Source

figshare

Collection Method

Laboratory experiments including checkerboard tests, time-kill assays, biofilm detection, and in vitro/in vivo model studies.

Freshness

Last updated 2026-05-25 06:48:34; freshness should be verified.