Single-Molecule AFM Observations of Cooperative Host-Guest Complexation on Surfaces

32.8 KB of text data from figshare, authored by Hitoshi Asakawa and last updated in May 2026. The dataset describes the direct observation of association-dissociation dynamics in densely assembled pillar[5]arene host structures using frequency modulation and high-speed atomic force microscopy. It reveals positive cooperativity in guest binding at solid-liquid interfaces.

Use Cases

• Modeling cooperative binding effects in supramolecular systems based on the described lateral host-host interactions.
• Benchmarking single-molecule imaging techniques against the described AFM observations of reversible complexation.
• Studying the dynamics of molecular association-dissociation at solid-liquid interfaces as described in the dataset.

Strengths

• Data is derived from direct, single-molecule level observations using two AFM techniques, as stated in the description.
• The dataset focuses on a specific, high-density assembly of pillar[5]arene host structures, providing a clear experimental context.

Limitations

• The dataset is very small at 32.8 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Observations generated using frequency modulation AFM and high-speed AFM techniques.

Freshness

Last updated 2026-05-20 08:09:46