Cough as an Adverse Effect for Inhalation Pharmaceutical Products

An article reviewing factors by which inhalation products may cause cough, authored by Rachel Yoon Kyung Chang from The University of Sydney. The work discusses how chemical or mechanical stimulants, inhaler device and drug types, dose, excipients, and formulation characteristics can trigger cough. It also examines how inflammatory mediators and bronchoconstriction can enhance the cough-provoking effect of aerosols.

Use Cases

• Analyzing cough triggers based on inhalation device and drug type mentioned in the description
• Modeling adverse effect risk based on formulation characteristics like pH and particle size
• Reviewing the physiological mechanisms of cough induction by aerosols for educational purposes

Strengths

• Authored by a researcher from a recognized academic institution, The University of Sydney
• Focuses on a specific and clinically relevant adverse effect in drug delivery

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

paperswithcode

Collection Method

Likely a literature review article.