In Vitro Blood-Brain Barrier Heatstroke Model Experiments with Dexamethasone

A dataset from figshare contains raw data, figures, and statistical analysis for creating an in vitro blood-brain barrier model under heatstroke conditions. The data includes preliminary experiments testing heat loads from 41°C to 43°C on different cellular models with varying stress durations. It was authored by Pichlerova and last updated in June 2026.

Use Cases

• Modeling blood-brain barrier permeability under hyperthermia based on in vitro cell culture data.
• Evaluating the therapeutic effect of Dexamethasone on heatstroke-induced cellular stress.
• Comparing cellular responses to different heat-stress durations (41-43°C) mentioned in the description.
• Performing statistical validation of experimental results using the included 2-way ANOVA and Šídák's multiple comparisons test.

Strengths

• Includes raw data from all preliminary experiments creating the heatstroke model.
• Contains complete statistical analysis results (2-way ANOVA, Šídák's multiple comparisons test).
• Covers a range of experimental conditions, including tests at 41°C, 42°C, and 43°C.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

In vitro experiments on endothelial cells and pericytes under controlled heat loads.

Freshness

Last updated 2026-06-01 21:56:03; freshness should be verified.