Cryo-EM Maps of Mitoribosomal Small Subunit Assembly Intermediates

Final cryo-EM maps from the article 'Mitoribosomal small subunit maturation involves formation of initiation-like complexes'. The dataset contains structures of middle and late assembly intermediates of the Trypanosoma brucei mitochondrial small subunit at 3.6 and 3.7 Å resolution. It was produced by Tea Lenarčič at ETH Zurich.

Use Cases

• Training deep learning models for cryo-EM density map segmentation based on the provided structural maps.
• Validating molecular dynamics simulations of ribosomal assembly using the high-resolution intermediate structures.
• Comparative structural analysis of ribosome assembly pathways across species using the identified assembly factors.

Strengths

• High-resolution structural data at 3.6 and 3.7 Å.
• Focuses on specific middle and late assembly intermediates, providing a snapshot of the process.
• Associated with a peer-reviewed publication in a scientific journal.

Limitations

• Row count and exact file formats are unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect the specific experimental and biological context of Trypanosoma brucei.

Provenance

Source

ETH Zurich

Collection Method

Cryo-electron microscopy