TRPM3 Ion Channel Cryo-EM Structure in Apo State

Cryo-electron microscopy data and atomic models for the TRPM3 ion channel from the manuscript "Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3". The 6.2 MB dataset, authored by Janine D. Brunner, was last updated on May 23, 2026. Files are provided in the Crystallographic Information File (CIF) format.

Use Cases

• Validate and refine atomic models of TRPM3 based on the provided Cryo-EM density.
• Analyze the ligand-binding pocket architecture described in the associated manuscript.
• Use the apo-state structure as a reference for molecular dynamics simulations of channel gating.

Strengths

• Data is directly linked to a peer-reviewed scientific manuscript, providing context and validation.
• Files are provided in the standardized CIF format, which is interoperable with structural biology software.
• The dataset is licensed under CC-BY-4.0, allowing for broad reuse with attribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred from the CIF format standard and manuscript.
• Row count is unknown, which may limit suitability assessment for certain computational tasks.
• The description metadata is limited to the title and source manuscript; detailed experimental parameters require consulting the paper.

Provenance

Source

figshare

Collection Method

Cryo-electron microscopy

Freshness

Last updated 2026-05-23 07:04:20; freshness should be verified for ongoing research.