VdPBP1 Protein Interactions and Terbinafine Resistance Data

49.8 KB of tabular data in XLSX format from a study on the cytochrome b5-like protein VdPBP1 in Verticillium dahliae. The dataset supports findings on how VdPBP1 mediates electron transfer in ergosterol biosynthesis to confer resistance to the fungicide terbinafine. It was authored by Huan Li and last updated in March 2026.

Use Cases

• Analyze protein interaction data between VdPBP1 and squalene epoxidase VdERG1 to model ergosterol pathway mechanisms.
• Correlate terbinafine dose-dependent inhibition levels with VdPBP1 protein expression data to study drug resistance.
• Examine data on hemin and cytochrome P450 reductase supplementation effects on ergosterol metabolism restoration in mutants.

Strengths

• Data is directly linked to a specific, peer-reviewed biological mechanism: VdPBP1's role in terbinafine resistance.
• Includes experimental results on protein interactions, drug inhibition, and metabolic restoration, providing multiple analytical angles.
• Dataset is structured in the widely accessible XLSX format, facilitating immediate analysis in common tools.

Limitations

• The dataset is very small at 49.8 KB, indicating limited scope and likely a small sample size unsuitable for large-scale statistical modeling.
• Specific data structure, column definitions, and row counts are not provided, complicating initial assessment of usability.
• Data is focused on a single fungal species (Verticillium dahliae), limiting generalizability to other organisms.

Provenance

Source

figshare, authored by Huan Li.

Collection Method

Experimental data from a study on fungal biology and fungicide resistance, likely involving molecular biology and biochemical assays.

Freshness

Last updated March 2026.