Hokyoung Kwak provides a genome-wide CpG coverage matrix derived from whole-genome bisulfite sequencing (WGBS) data of human brain tissue samples. The 1.2 GB TSV file contains coverage values representing sequencing depth at union CpG sites shared across all analyzed samples. The data was generated after read alignment to the GRCh38 human reference genome and processed using a standardized WGBS workflow.
Use Cases
- Analyze DNA methylation patterns across the genome based on CpG site coverage.
- Compare methylation levels between different brain tissue samples based on shared CpG sites.
- Train models for epigenetic feature prediction based on genome-wide bisulfite sequencing data.
Strengths
- Data is genome-wide, covering union CpG sites across all samples.
- Processed against the GRCh38 human reference genome, a standard in the field.
- Generated using a standardized whole-genome bisulfite sequencing (WGBS) workflow.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- Data may reflect bias inherent to the specific brain tissue samples and sequencing platform used.
Provenance
- Source
- Hokyoung Kwak via figshare
- Collection Method
- Derived from whole-genome bisulfite sequencing (WGBS) data after read alignment and CpG site extraction.
- Freshness
- Last updated 2026-05-12 04:44:59; freshness should be verified.