Human Dermis CpG Methylation Coverage Matrix from Whole-Genome Bisulfite Sequencing

1.2 GB genome-wide CpG coverage matrix derived from whole-genome bisulfite sequencing of human dermis tissue. The data was processed by Hokyoung Kwak, including bisulfite alignment to the GRCh38 reference genome and duplicate removal, and was last updated in May 2026. Coverage values indicate sequencing depth across union CpG sites identified from all analyzed samples.

Use Cases

• Analyze genome-wide DNA methylation patterns in human dermis based on CpG coverage values.
• Compare sequencing depth and coverage uniformity across CpG sites identified from multiple samples.
• Investigate epigenetic regulation in skin biology using data aligned to the GRCh38 reference genome.

Strengths

• 1.2 GB of processed sequencing data provides substantial coverage information.
• Data processing included adapter trimming, bisulfite alignment to GRCh38, and duplicate removal, suggesting a standardized analysis pipeline.
• The dataset is licensed under CC-BY-4.0, allowing for broad reuse.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for specific analyses.
• The description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Hokyoung Kwak via figshare

Collection Method

Whole-genome bisulfite sequencing (WGBS) of human dermis tissue samples.

Freshness

Last updated 2026-05-12 04:45:42