Human Heart Tissue CpG Coverage Matrix from Whole-Genome Bisulfite Sequencing

A 1.2 GB TSV file contains genome-wide CpG coverage profiles generated by whole-genome bisulfite sequencing of human heart tissue. The matrix summarizes CpG site-level sequencing coverage across union CpG loci identified in the analyzed samples. Author Hokyoung Kwak published the dataset on figshare under a CC-BY-4.0 license, last updated on 2026-05-12.

Use Cases

• Analyze DNA methylation patterns in heart tissue based on CpG site-level coverage profiles
• Identify differentially methylated regions in the human genome based on CpG loci coverage
• Perform epigenetic association studies for cardiac traits based on genome-wide methylation data
• Benchmark methylation calling algorithms based on whole-genome bisulfite sequencing coverage

Strengths

• Dataset size is 1.2 GB, indicating substantial genomic coverage
• Data is shared under a permissive CC-BY-4.0 license
• Last updated timestamp of 2026-05-12 suggests recent availability

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Description metadata is limited; actual data quality requires manual inspection after download

Provenance

Source

figshare

Collection Method

Whole-genome bisulfite sequencing (WGBS) analysis of human heart tissue samples

Freshness

Last updated 2026-05-12 04:46:25